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Since its discovery, the effectiveness of molecular hydrogen in various diseases, such as ischemiareperfusion injury 8 , IBD 9 , and hepatitis 10 has been reported

High levels of oxidative stress can lead to inflammatory conditions (diabetes, cardiovascular disease and autoimmune disease) and illnesses such as cancer

Whether those effects run through GHIGF-1 signaling, direct GHSR-1a activation in cardiomyocytes, or some combination remains an active question

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