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Diarrhea: Affects a significant percentage of patients, especially during the first few weeks at a new dose
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14 According to our patent searches, Novo Nordisk has filed 91 patents for formulations, 41 patents covering devices to deliver the drug, and 45 patents for methods of treatment (Figure 6)
HEK293T cells were transfected with 1 g lentiCRISPRv2 containing the sgRNA insert, 0.67 g psPAX2 (Addgene, 12260) and 0.33 g pVSVg (Addgene, 8454) using 6 g polyethylenimine (Sigma-Aldrich, 919012) in Opti-MEM (Thermo Fisher, 31985062)
