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Immunology and Allergy Clinics of North America 1991;11:611633

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B12 supplements can interact with certain medicines, including: Chloramphenicol (Chloromycetin Sodium Succinate) Proton pump inhibitors Metformin (Glucophage, Glumetza, Riomet) Gastric acid inhibitors If youre taking any of these medications, talk to your doctor or pharmacist before starting a B12 supplement