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The risk of developing nAMD appeared to increase the longer a patient was exposed to the medication, he continued
A dedicated cardiovascular outcomes trial (CVOT) for orforglipron has not been mandated by the FDA for initial approval but may be required or conducted voluntarily as a post-marketing commitment, following the precedent set by the SELECT trial for semaglutide
But the evidence shows: Pancreatitis is rare Most cases are not caused by GLP-1s Gallstones and rapid weight loss are more likely culprits The benefits of GLP-1 therapy for obesity and diabetes are significant With proper supervision, GLP-1 medications remain safe and effective tools in managing chronic metabolic disease.
Dr Sands said the finding that greater loop gain predicted treatment effectiveness was initially surprising
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