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Patients with glutathione synthetase deficiency accumulate the dipeptide -glutamylcysteine and cysteine in fibroblasts [24]

Standard protocols appear well-tolerated in this demographic, with the 15-year follow-up study providing reassurance about long-term use in older individuals

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Briefly, the complex was assembled in the excess peptides and solubilized in LMNG/CHS and purified using M1 anti-Flag affinity resin and SEC