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the second part of the trial (part II) was an exploratory multiple-dose assessment in healthy postmenopausal females and healthy adult males (Fig

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51 The exposure from consecutive doses was overlapped and day-to-day variability in oral absorption was reduced by the once-daily dosing and long t 1/2 , resulting in stable steady-state concentrations of oral semaglutide

1780, n o 11, 1236-1248 (PMID 18395526, DOI 10.1016/j.bbagen.2008.03.006, lire en ligne)