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Ten months earlier, the Phase 3 Exenatide-PD3 trial had reached the same conclusion in Parkinsons disease: no effect on progression across 194 patients followed for 96 weeks, with no treatment difference on dopamine-transporter imaging in the trials imaging substudy [2]

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If the etiology of the oral pigmentation cannot be clinically established, a tissue biopsy is warranted for definitive diagnosis