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The diagnostic criteria for hypertension were an average systolic blood pressure (SBP) 140 mmHg or diastolic blood pressure (DBP) 90 mmHg (measured three times at 5-min intervals), or 24-h SBP 130 mmHg or 24-h DBP 80 mmHg, or a history of hypertension with treatment using antihypertensive medications (12)

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Shlipak MG, Matsushita K, Arnlov J, et al

The main outcome measures, monitored every 3-6 months, were linear growth enhancement (height velocity), bone age progression, and safety measures including clinical chemistry

GHK-Cu supplies the extracellular matrix remodeling via collagen, glycosaminoglycans and the MMP-TIMP system as well as an antioxidant and growth-factor-inducing component