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doi: 10.1016/j.biopha.2020.111104 51 LeeJ-HBaekSYJangEJKuSKKimKMKiSHet al
The BF16F10 melanoma cell line is the most widely used model for tumor-bearing mice (Fig
and caveolin-1 (CAV1), a scaffold protein of caveolar membranes involved in signal transduction and in the uptake of lipophilic compounds, which directly interacts with NRF2, probably competing with KEAP1 for binding to NRF2, and subsequently suppresses its transcriptional activity [231]
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In addition to behavioral therapies, pharmacological approaches have demonstrated potential benefits
