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10.3390/ani12151946 79 WengF
This guide covers the full reconstitution process for subcutaneous injection
Reference: Goldstein AL et al
The international strain name is C57BL/6NTac-Gclctm1a(EUCOMM)Wtsi/WtsiCnbc
RSL3 binds to the nucleophilic active site of GPX4, and then reduces the expression level of GPX4 most effectively through chloroacetamide moiety (Jelinek et al., 2018), thus inactivating GPX4, producing lethal ROS accumulation and inducing ferroptosis
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