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Potential antidepressant effects
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Therefore, in peri- and post-menopausal patients, rapid or substantial weight loss while on semaglutide may plausibly unmask or intensify GSM symptoms via endocrine and tissue-level changesalthough the specific contribution of semaglutide vs weight loss per se is not established
Developed steatosis further stimulates de novo lipogenesis, a characteristic feature of MASLD patients, while concurrently reducing lipid efflux in the form of high-density lipoprotein (HDL) particles due to insufficient apoB protein synthesis [33]
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Exercise, as a vital non-pharmacological intervention, holds great promise in preventing, treating, and rehabilitating NDDs, as it can directly or indirectly suppress ferroptosis and mitigate NDD progression by regulating iron metabolism, oxidative stress, and exerkines expression
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