Microbial metabolites such as SCFAs and tryptophan catabolites can influence brain function directly or via modulation of systemic inflammation
Notably, numerous studies have demonstrated that DMF alleviates cognitive and motor dysfunction by mitigating neurodegeneration, oxidative stress, and neuroinflammation in rodent models of Parkinsons disease (PD) [56], AD [57, 58], frontotemporal dementia [59], traumatic brain injury (TBI) [60], and ischemia [61]
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