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After propensity-score matching, the two cohorts (26,670 in each cohort, mean age 58.0 years, 45.3% women, 14.7% black, 60.3% white, 6.5% Hispanic) were balanced (Supplementary Table 1)
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[5] [7] These effects can lead to reduced food and fluid intake, which may contribute to dry moutha potential risk factor for bad breath
FXR knockout mice show increased CYP7A1 expression and hepatic BA synthesis, suggesting that FXR primarily mediates the inhibitory effects of BA synthesis via CYP7A1 (Sinal et al., 2000)
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