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New biologics and targeted therapies in SLE target a broad spectrum of key immune players, including B/T lymphocytes, plasmacytoid dendritic cells (pDC), plasma cells, T/B cell co-stimulation molecules, cytokines or their receptors, and various intracellular signaling pathways
After full depression, count to 3 before withdrawing the needle
Synthetic biology-inspired strategies and tools for engineering of microbial natural product biosynthetic pathways
Individuals with null genotypes for GSTM1 or GSTT1 (i.e., they lack functional copies of these genes) exhibit a markedly different pharmacokinetic profile
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