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These exerkines act through autocrine, paracrine, or endocrine mechanisms to mediate inter-organ communication, playing essential roles in regulating nervous system function, attenuating neuroinflammation, and promoting neural repair (Pedersen and Fischer, 2007)

PLoS One 12(11):e0187351 Zmock M, Hofbauer S, Schaffner I, Gasselhuber B, Nicolussi A, Soudi M, Pirker KF, Furtmller PG, Obinger C (2015) Independent evolution of four heme peroxidase superfamilies

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