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And ironically, many of them end up having to slow down or pause treatment to recover, losing more time than if they had followed the schedule in the first place

doi: 10.1002/cncr.22638 28 SchmitzKHTroxelABDeanLTDeMicheleABrownJCSturgeonKet al

Inclusion and exclusion criteria We included potentially relevant studies if they met the following inclusion criteria: (a) original randomised clinical trials with either parallel or cross-over design