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These remedies either decrease melanin production or dispose of layers of the pores and skin where melanin is focused
A 2017 review summarised neuroprotective properties of silymarin in animal models, including: Reduction of amyloidogenic activity (relevant in Alzheimer's research) Anti-inflammatory action in nerve tissue Reduction of oxidative stress in the brain Possible positive effects on cognitive function Possible reduction of stroke risk Whether these effects can be achieved in humans at attainable concentrations of silymarin in particular whether sufficient quantities can cross the blood-brain barrier remains unclear
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Adv Pharmacol 38: 6578
Ren et al., 1999
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