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The GLP-1 RAs marketed in our country that have shown renal benefits (liraglutide, semaglutide, and dulaglutide) can be administered with GFR of 15mL/min/1.73m2.132 Pharmacokinetics studies indicate that in CKD G5 it does not increase the area under the curve, not even in dialysis patients

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Dosage: Starting dose: 2.5 mg once weekly

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ROS-dependent signal transduction

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