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By integrating data across trials and modeling continuous doseresponse relationships, the present analysis provides a more granular understanding of how these agents compare across the full range of clinically relevant doses

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"In this study, 18.7% (nearly 1 in 5) patients who had these issues still had not recovered by the end of the study (it is unclear how many of those had stopped the medication or not), so that is something that will require further studies to be better characterized." Ali noted that the recommended dose by the Food and Drug Administration (FDA) for a semaglutide drug is 2.4 mg taken weekly, so a higher dose would be outside those boundaries