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Dementia is not a single disease but a group of conditions that affect: Memory Thinking and reasoning Communication Ability to perform daily self-care People are at higher risk for dementia if they have certain medical conditions, including: Type 2 diabetes Obesity Heart disease A history of strokes or mini-strokes Because semaglutide directly improves several of these conditions, researchers are investigating whether it could also reduce dementia risk

For women, evaluation of estradiol levels or assessment for genitourinary syndrome of menopause may be appropriate

Parkin deficiency may affect the microglial inflammatory activation by enhancing NF-B-dependent NLRP3 activation (153)

This post builds on an emerging theme on PainScience.com: metabolic risk factors for pain