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One of the most well-known studies found that patients taking 0.5 mg of tesofensine daily lost up to 26 pounds in 24 weeks
Yoon KH, Kang J, Kwon SC, Trautmann ME, Hompesch M, Stewart J, Sorli CH (2020) Pharmacokinetic and dose-finding studies on efpeglenatide in patients with type 2 diabetes
In the SUMMIT HFpEF trial, a 38% lower risk of cardiovascular death or worsening heart failure was reported, alongside changes in cardiometabolic and lipid markers
Its almost always traded off against efficacy
While this a frustrating side effect, you can take comfort in knowing that youre not alone
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