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The OB is a structure capable of detecting numerous metabolic signals
(2015): in studies of drugs approved between 2010 and 2012, just 45 percent of trial participants in small molecule trials were women, but they represented 65 percent of participants in biologic trials (based on Drugs@FDA data)
doi:10.1016/j.molmet.2020.101090 Nauck MA, Meier JJ
The mechanism involves multiple pathways working simultaneously
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