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Lee DY, Song MY, Kim EH (2021) Role of oxidative stress and Nrf2/KEAP1 signaling in colorectal cancer, mechanisms and therapeutic perspectives with phytochemicals

doi: 10.11118/actaun201260080019 28 BonaE.LinguaG.ManasseroP.CantamessaS.MarsanoF.TodeschiniV.et al

Some research suggests that Epithalon may influence pineal gland activity, potentially affecting melatonin synthesis and secretion patterns

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For instance, ApoE -/- mice fed with high cholesterol diet supplemented with ellagic acid (EA) exerts an atheroprotective effect by improving the antioxidant capacity, attenuated hypochlorous acid (HOCl)-induced endothelial dysfunction and increased the expression of HO-1 and Nrf2 (Yang et al., 2018b)