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Studies in mice have shown that a high concentration of IgG2a is indicative of a Th1 response, while IgG1 presence suggests a Th2 response ( The challenges associated with interpreting murine spleen CFU data after aerosol challenge have previously been highlighted ( MTB infection, but this protection did not extend to the spleen
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doi:10.2165/00044011-199815020-00001
International Journal of Clinical and Experimental Pathology, 8 , 38193826
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