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Intriguingly, PIK3C3/VPS34 lactylation augments its interaction with Beclin1, Atg14L, and UVRAG, increasing its lipid kinase activity and promoting macroautophagy/autophagy and endolysosomal degradation
Why These Limitations Matter for Interpretation Taken together, the limitations mean GHRP-2 should be understood as a scientifically important and well-characterized research compound genuinely valuable for what it taught endocrinology about the ghrelin/GHS-R1a system, and genuinely useful as a diagnostic probe but not as a validated therapy
ISSN 0149-5992
10.1016/j.micpath.2007.09.002 46 VermaA.KaurM.SinghL
However, the evidence for PRP is somewhat stronger, and it has been used more extensively in clinical practice
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