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Thyroid C-Cell Tumors: In mice and rats, semaglutide (the active ingredient in Wegovy and Ozempic) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)
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The study found that semaglutide use was not associated with an increased risk of neurological or psychiatric conditions compared to the other antidiabetic drugs
A key differential side effect for Retatrutide is a transient, dose-dependent increase in heart rate observed in the clinical trials, which necessitates careful cardiac screening and monitoring by a supervising physician
[1] [3] However, the gastrointestinal effects of these drugsincluding nausea, vomiting, diarrhea, and constipationcan potentially affect nutrient absorption and electrolyte balance
