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For manufacturers, this presents a dilemma
Currently, in addition to LY3463251, several other GDF-15 agonists are being assessed in early-stage clinical trials, including NNC0247-0829 and JNJ-9090/CIN-109, among others
The protein levels in the homogenate were assayed using protein assay reagent (Bio-Rad, Hercules, CA) to normalize the amount of lipid extracted
For severe deficiency, clinicians typically prescribe loading doses daily or every other day for one to two weeks followed by monthly maintenance injections
According to market research company Mintel, in the US, 15% of adults who currently claim to be managing their weight are using GLP-1 medications
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