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They skew urban at 41% versus 28% in the general population

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It shifts across puberty, reproductive years, pregnancy, perimenopause, menopause, and aging, and each stage changes the pattern in a different way

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Gastrointestinal side effects led to treatment discontinuation in 10% of semaglutide patients versus 2% on placebo, though serious adverse events were actually less frequent with semaglutide (33.4% vs 36.4%)