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The development of generic alternatives of GLP-1 agonists by several pharma companies increases the accessibility for many people, helping them to reduce weight

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However, Rybelsus may lead to greater weight loss (8-11% body weight reduction) compared to Trulicity (3-5%), while Trulicity has specific FDA approval for cardiovascular risk reduction in adults with established cardiovascular disease or multiple cardiovascular risk factors

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Muscle Growth and Preservation Increased GH and IGF-1 levels stimulate protein synthesis, promoting muscle hypertrophy and reducing muscle catabolism