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In a pre- and postnatal development study in pregnant Sprague Dawley rats, SNAC was administered orally at 1,000 mg/kg/day (exposure levels were not measured) on Gestation Day 7 through Lactation Day 20

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Specific research areas include: Regulation of nitric oxide and endothelial signaling pathways Actin dynamics and cell migration processes Extracellular matrix deposition and remodeling Oxidative stress mitigation and redox balance Modulation of gene expression related to repair and immune signaling The combined formulation allows for the evaluation of overlapping and divergent signaling effects without the need for parallel administration protocols

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BMC Nephrol 26(1):230