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Graphical Abstract 1 Introduction Reactive oxygen species (ROS) are a group of highly reactive, short-lived oxygen-containing molecules that are present in both biological systems and the environment (Spanolios et al., 2024)

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GHK-Cu stimulates collagen I, III, and elastin synthesis in fibroblasts Promotes decorin and glycosaminoglycan production for matrix integrity Attracts immune cells and promotes wound debridement and repair GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes2012Gene Expression Gene expression analysis reveals GHK-Cu upregulates antioxidant genes and downregulates pro-inflammatory genes, suggesting a protective role against oxidative stress and UV damage in skin

Repurposing of high-dose N-acetylcysteine as anti-inflammatory, antioxidant and neuroprotective agent in moderate to severe traumatic brain injury patients: a randomized controlled trial

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