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Cagrilintide is a long-acting amylin agonist that has 84% homology to native human amylin with several amino acid substitutions and other chemical alterations to enhance stability, potency and biological half-life [3, 6]

Pregnancy and breastfeeding represent situations where no safety data exists

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Benefits were more pronounced in studies using 6001,200mg per day over at least eight weeks.2 A 2022 randomized controlled trial in patients with metabolic syndrome found that 600mg of ALA daily for 12 weeks significantly reduced triglyceride levels and total cholesterol compared to placebo.59 However, the study did not observe significant changes in LDL-C or HDL-C

Both methods of administration have advantages and disadvantages, and the choice is influenced by factors such as personal preferences, treatment objectives, and medical concerns