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Noetel M, Sanders T, Gallardo-Gmez D, Taylor P, Del Pozo Cruz B, van den Hoek D, et al
doi: 10.3389/fncel.2020.00221
Individual responses vary considerably, and the GLP-1 elevations observed are generally modest and transient compared to pharmaceutical GLP-1 medications
A 2005 study demonstrated that both peptide and non-peptide GH secretagogues act through the GHS-R1a receptor but can also function as ghrelin receptor ligands with distinct binding properties, suggesting potential differences in downstream signaling despite shared receptor engagement
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