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Warnings and precautions include severe gastrointestinal adverse reactions, acute kidney injury, acute gallbladder disease, acute pancreatitis, serious hypersensitivity reactions, increased risk of hypoglycemia with concomitant use of an insulin secretagogue or insulin, diabetic retinopathy complications in patients with type 2 diabetes, suicidal behavior and ideation, and pulmonary aspiration during general anesthesia or deep sedation

The dosage of AOD9604 used in this study or 0.25 mg per injection, was carefully calculated to be molar equivalent to doses of full-length GH shown to be effective in prior rabbit OA studies

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A 500mcg dose is 10 units