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Not only do NETs and their components (histones, DNA, and myeloperoxidase) directly damage endothelial cells, but their synergistic effects with oxLDL or native LDL further enhance endothelial-to-mesenchymal transition (EndMT), leading to endothelial cell dysfunction and promoting neovascularization, which influences AS progression [285]
[1] [2] These medications include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and others
It is recommended to take the injection on the same day each week, at any time of day, regardless of meal timing
& Yoo, H
Gastrointestinal nitric oxide generation in germ-free and conventional rats
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