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Autologous chondrocytes and mesenchymal stem cells have been studied for cartilage regeneration, but for cell injection therapy, the main issue is the rapid clearance of transplanted cells due to lack of adhesion to cartilage defects (Huey et al., 2012

Naturally occurring copper tripeptide that activates fibroblasts to upregulate collagen I/III/IV and elastin synthesis, inhibits MMP-1/2/9 collagen degradation enzymes, activates lysyl oxidase for collagen cross-linking, stimulates wound bed angiogenesis via VEGF/FGF-2, and activates Nrf2 antioxidant response element genes

In addition, we applied flow cytometry to demonstrate that RT can be used for high-throughput quantification of GSH levels in single cells

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