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Progressive decrease of melatonin production over consecutive days of simulated night work

Del Prato S, Kahn SE, Pavo I et al (2021) Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial

This study utilized a randomized, placebo-controlled, double-blind, multicenter study design, a full 10-week supplementation, blood monitoring at baseline and posttreatment, and multiple assessments of various functions

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However, oral peptide supplements are becoming more available for at-home use