Data availability The EHR database used in this study were obtained from TriNetX ( Abbreviations GLP-1RAs: Glucagon-like peptide-1 receptor agonists T2DM: Type 2 diabetes mellitus EHRs: Electronic health records SGLT2: Sodium-glucose cotransporter-2 DPP-4: Dipeptidyl peptidase-4 HR: Hazard ratios CI: Confidence intervals References Alfaris N, Waldrop S, Johnson V, Boaventura B, Kendrick K, Stanford FC (2024) GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review
In a mid-stage trial, nearly three-quarters of patients experienced nausea, nearly half experienced vomiting, and an much as a quarter experienced diarrhea numbers the company considered too high to convince people to take its drug twice every day
However, the FDA still must review the actual application and determine whether the statutory and regulatory requirements for licensure are satisfied
Seek medical advice if you experience two or more consecutive missed periods, severe pelvic pain, abnormal bleeding, or signs of pregnancy
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