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Age, sex, and genetic factors may also influence response, though these were not primary endpoints in early studies

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In mice fed HFD, TMAO supplementation exacerbated glucose intolerance, induced adipose tissue inflammation, and promoted insulin resistance (154)

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EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

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Glucomannan (Konjac Root Fiber) Mechanism : Glucomannan is a soluble fiber derived from the konjac plant

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Souverein et al., Incidence and Determinants of Sildenafil (dis)continuation: the Dutch Cohort of Sildenafil Users

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