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Description

In metabolic diseases, lean adipose tissue macrophage-derived exosomes (ExosLean) deliver miR-222-3p to target the inflammatory factor Bcl2l11/Bim, promoting macrophage polarization toward a reparative M2 phenotype in diabetic wounds and accelerating tissue healing (303)

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One study replicated such positive findings in non-human primates 78

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Exenatide stretched that measure to about 2.5 hours3 sufficient for therapy but requiring twice-daily injections that placed a significant burden on patients

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