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10.1038/mp.2017.255 233 ZarateC
Molecular analysis using Western blot techniques suggested increased phosphorylation of p21-activated kinase and paxillin following exposure to BPC 157, while total protein expression levels remained unchanged
They are considered a non-heritable group of persister cells because they do not contain stable mutations, unlike the resistant mutant forms of fungi, which result in an increased minimal inhibitory concentration (MIC)
Similar findings have been reported in other trials, with EA consistently demonstrating a favorable safety profile (84, 87)
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