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The rationale for the combination is based on extrapolation from the established anti-nausea evidence, the known neurotransmitter mechanisms, and anecdotal reports from clinicians and patients who use the compounded formulation

In addition to severe stomach-related side effects, taking extra or unpredictable amounts can result in problems such as incorrect dosing

PBMs have significant lobbying resources and existing relationships with state insurance regulators

Waste and Environmental Impact: Chemical peptide synthesis is inherently solvent-intensive

While this therapy presents a viable option for many, certain circumstances warrant caution or exclusion