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7-Methylation of chenodeoxycholic acid derivatives yields a substantial increase in TGR5 receptor potency

As your body adjusts after weight loss, you may not need as much food as you did before

Cumulative food intake and body weight reduction with either of the agonists were no different from vehicle (Fig

Dose-response analysis indicates optimal benefits occur after approximately 50 weeks of continuous supplementation, suggesting long-term metabolic remodeling rather than acute effects

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