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Strumila R, Lengvenyte A, Guillaume S, Nobile B, Olie E, Courtet P
Mitchells accomplishments were many but one was very personal
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George Westinghouse bought patents from Nikola Tesla, and undertook illuminating the nation while Tesla, the lone genius, struggled with poverty
no establecida en humanos Farmacocintica : Potencialmente variable debido a diferencias en grosor cutneo, flujo sanguneo, hidratacin y temperatura Ventajas tericas : No invasiva, potencialmente mejor adherencia, evita metabolismo de primer paso heptico Desafos : Tamao molecular grande, degradacin enzimtica cutnea, irritacin local, rea de aplicacin requerida potencialmente grande Desde una perspectiva de seguridad del paciente, las formulaciones actualmente aprobadas ofrecen control de dosis preciso y resultados clnicos predecibles
