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Connective Tissue and Whole-Body Repair GHK-Cu was first discovered in human albumin in 1973, where it prompted old liver cells to function like younger cells

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Clinically, the weight-lowering effect of metformin is partially mediated by elevated circulating GDF15 levels

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The clinical drug development program was halted in 2007 after the pivotal Phase IIb trial did not show statistically significant weight loss in the primary endpoint