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The mechanism operates through two distinct pathways: direct NF-B inhibition via MC1R-coupled G-protein signalling, and secondary modulation of mast cell degranulation that reduces histamine-mediated inflammation
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Mitochondrial dysfunction occurs in all individuals with age (211)
The central role of Ca 2 as a secondary messenger underscores its versatility in encoding stress-specific information through distinct spatial and temporal patterns
Andersen RE, Wadden TA, Bartlett SJ, Vogt RA, Weinstock RS
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