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Important safety information includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), risk of pancreatitis, gallbladder disease, and hypoglycemia when used with insulin or insulin secretagogues

With such a high prevalence, type 2 diabetes is associated with an annual cost of 1.3 billion in the Netherlands

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Compounding pharmacies create tirzepatide formulations when brand-name medications face shortages, mixing tirzepatide powder into injectable or sometimes oral forms