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2.5 Disrupted proteostasis and autophagy-lysosomal dysfunction The autophagy-lysosomal pathway (ALP) and ubiquitin-proteasome system (UPS) are critical for degrading misfolded proteins

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de Boer IH et al (2022) Diabetes management in chronic kidney disease: a consensus report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO)

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You can help your body maintain its glutathione stores by including specific foods in your diet

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We actually prefer SQ because its painless and has an established track record of effective B12 delivery, whereas IM can be painful and tends to put people off self-injecting

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