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Glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus and nonalcoholic fatty liver diseaseCurrent background, hopes, and perspectives

The medication builds up in your system over four to five weeks of consistent dosing until it reaches what pharmacologists call "steady state," a stable concentration that remains relatively constant between doses

That overall rate was actually lower in the ipamorelin arm, though the study was not powered to detect safety differences

That can take as little as two weeks or as long as three months

However, with an emphasis on safety and tolerability in humans, it did not aim to conclude with any significant new findings, but rather to support earlier ones