105,106,326 Targeting key signaling pathways, such as TGF-, Wnt, and Notch, and EMT-related transcription factors (e.g., ZEB1, TWIST1) is another strategy under active investigation
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Additionally, environmental factors such as iodine excess or deficiency, smoking, stress, exposure to chemicals, medications (e.g., amiodarone, interferon-), and some viral/bacterial infections can alter gene expression patterns through epigenetic mechanisms and trigger autoimmune processes
Dihexa is an oligopeptide derivative derived from angiotensin IV that has drawn significant interest in neurobiology and synaptogenesis research
L-Carnitine is an essential nutrient in lipid metabolism, which promotes the transportation of long-chain-fatty-acids across the mitochondrial membrane, thus allowing the cells to break down fat and release energy from reserves of stored fat [6, 7]